Orexa is a clinical-stage pharmaceutical company that develops therapeutics to increase food intake. Its lead compound is a proprietary oral formulation for human use, based on a well known anesthetic.

The company has started its first and second phase 2a study, in the prevention of Post-Operative Ileus and Anorexia Nervosa, with expected first inclusion of patients in October 2023 and Q1-2024.

Further, it is in preparation of a third phase 2 study in Cachexia. In all these three indications increased food intake could lead to an improved patient health, a shorter hospital stay and significant cost savings.

Orexa was founded in 2016 and is headquartered in Herpen (Oss Region, Noord Brabant), The Netherlands.


Sake Stevenhaagen

Sake Stevenhaagen



Actuarial Sciences (University of Amsterdam)



Early investor in AM-Pharma.

CFO of Alloksys Life Sciences

Venture Partner of NextStage Early Stage Fund

Ard Peeters

Ard Peeters

CSO / Founder of Orexa

PhD in Psychology
Professor in Behavioural Pharmacology (Radboud UMC, Nijmegen)



Organon, Schering Plough, MSD

Within Organon Ard was responsible for the development of brain active (CNS) drugs.

“We have found a very strong signal in our pre-clinical research and successfully completed a Phase 1 study.

Now we are in the most exciting stage: will our mechanism of action also work in patients in Phase 2 ?”

Prof. Dr. Ard Peeters

CSO and founder of Orexa

Developing a medicine that increases food intake.